Seybold Report ISSN: 1533-9211
S Manohar Manikya Prabhu, Dr. Shiv Brat Singh
Vol 18, No 11 ( 2023 ) | Licensing: CC 4.0 | Pg no: 493-501 | Published on: 30-11-2023
Abstract
Many fields, including chemistry for medicinal use, agricultural chemicals, and materials science, are interested in the synthesis of novel five-membered heterocycles. In this study, we detail a flexible method for constructing such heterocyclic compounds, with -oxoketene dithioacetals serving as the central building blocks. Because of their adaptability as building blocks, a number of different synthetic routes can be facilitated by -oxoketene dithioacetals. The relevance of this synthetic method is demonstrated by its use in a wide range of fields. The availability of novel scaffolds for the creation of drugs aids medicinal chemistry, and the discovery of newly functionalized molecules aids agrochemical studies. The heterocyclic structures that have been synthesized are useful in the development of new electrical and optoelectronic materials. Dithioacetals provide a flexible and powerful method for synthesizing five-membered heterocycles from -oxoketene. The successful use of this strategy has the potential to transform industries by contributing to pharmaceuticals, agriculture, and innovative materials, in addition to enriching chemical variety.
Keywords:
Five-membered heterocycles, beta-oxoketene dithioacetals, pharmaceuticals, agricultural compounds, and structural materials.