Seybold Report ISSN: 1533-9211
Vetri selviSubramaniyan1, AnithaAkilan2, K. Revathi2, priyankadevi3, Senthilkumari4 and Suresh Dhanaraj* 1Department of Microbiology, School of Life Sciences, Vels Institute of Science, Technology, and Advanced Studies (VISTAS), Pallavaram, Chennai, 600 117 Tamil Nadu, India. 2 Professor and Former Director of Research, Meenakshi Academy of Higher Education and Research, Chennai – 600078, Tamil Nadu, India. 2 Meenakshi Academy of Higher Education and Research, Chennai – 600078, Tamil Nadu, India. 3 Guest faculty, JNRM College, Port Blair. 4Assistant professor; Head of department of zoology, Chellammal College *Department of Microbiology, School of Life Sciences, Vels Institute of Science, Technology, and Advanced Studies (VISTAS), Pallavaram, Chennai, 600 117 Tamil Nadu, India.*Corresponding Author
Vol 17, No 10 ( 2022 ) | DOI: 10.5281/zenodo.7221755 | Licensing: CC 4.0 | Pg no:1890-1898 | Published on: 18-10-2022
Abstract
The focus of this research was to determine the distribution of pathogenic organisms recovered from outpatients in the Chennai region of India, as well as their antibiotic susceptibility in vitro. A total of 745 urine samples were evaluated, with 340 (45.63 percent) showing signs of substantial bacterial growth. Urinary Tract Infections were identified based on positive culture growth. The Kirby-Bauer disc diffusion method was used to determine bacterial species and antimicrobial resistance of bacterial isolates against various popular antibiotics. From 340 instances, about 7 distinct types of uropathogens were discovered. E. coli, 139 isolates (40.8 %); Klebsiella spp, 86 isolates (25.2 %) Proteus spp., 61 isolates (17.9 %); Pseudomonas spp., 24 isolates (7%) coagulate negative Staphylococci spp (CNS), 12 isolates (3.5%) S. aureus. 11 (3.2%) isolates; Candida spp 7 isolates (2.0%).High resistance to Ampicillin, Erythromycin, Tetracycline, Ceftriaxone. Imipenem was indeed the antibiotic with the highest activity against isolated pathogenic organisms and the lowest resistance rate.
Keywords:
Urinary tract infections, antibiotic resistance, Imipenem, Amikacin, E. coli.